|
1 / 1
|
DeCS
|
|
 |
|
Descriptor English:
|
|
Thyroid Hormone Resistance Syndrome
|
|
Descriptor Spanish:
|
|
Síndrome de Resistencia a Hormonas Tiroideas
|
|
Descriptor Portuguese:
|
|
Síndrome da Resistência aos Hormônios Tireóideos
|
|
Synonyms English:
|
|
Generalized Resistance to Thyroid Hormone
Generalized Thyroid Hormone Resistance
Hormone Resistance, Thyroid
Refetoff DeWind DeGroot Syndrome
Refetoff Syndrome
Refetoff-DeWind-DeGroot Syndrome
Resistance, Thyroid Hormone
Syndrome, Refetoff
Syndrome, Refetoff-DeWind-DeGroot
Thyroid Hormone Resistance
|
|
Tree Number:
|
|
C19.874.410.500
|
|
Definition English:
|
|
An inherited autosomal recessive trait, characterized by peripheral resistance to THYROID HORMONES and the resulting elevation in serum levels of THYROXINE and TRIIODOTHYRONINE. This syndrome is caused by mutations of gene THRB encoding the THYROID HORMONE RECEPTORS BETA in target cells. HYPOTHYROIDISM in these patients is partly overcome by the increased thyroid hormone levels. |
|
Indexing Annotation English:
|
|
differentiate from EUTHYROID SICK SYNDROME where a non-thyroid disease is also present
|
|
See Related English:
|
|
Euthyroid Sick Syndromes
|
|
History Note English:
|
|
95
|
|
Allowable Qualifiers English:
|
|
|
|
Record Number:
|
|
32006
|
|
Unique Identifier:
|
|
D018382
|
Occurrence in VHL:
|
|
|
Similar:
|
|
DeCS
|